Haemorrhage alleviation with tranexamic acid - Intestinal system
Chief Investigator: Ian Roberts
Principle Investigator (LTHT): Dr Simon Everett and Dr Taj Hassan
Site: St James's University Hospital
This trial is shared between A&E and Gastroenyrology
Start Date: February 2014
End Date: May 19
The HALT-IT trial will determine the effect of early administration of tranexamic acid on mortality, morbidity (re-bleeding, non-fatal thromboembolic events), blood transfusion, surgical intervention and health status in patients with significant GI bleeding.
- The HALT-IT trial is a large, international, randomised, placebo controlled trial among 8,000 patients with GI bleeding.
- Eligibility criteria
- All adults with acute significant upper or lower gastrointestinal bleeding where the responsible clinician is substantially uncertain as to whether or not to use tranexamic acid, will be eligible
- Treatment will be allocated randomly